Katherine Marie Heigl

Katherine Marie Heigl (born November 24, 1978) is a Golden Globe-nominated American actress. Heigl is known for her roles on the TV series Grey's Anatomy and in the film Knocked Up.

In 2005 Heigl was cast in what would become her most high-profile role, as intern Dr. Isobel "Izzie" Stevens on Grey's Anatomy, an ABC medical drama. The show, originally introduced as a midseason replacement, has become a huge ratings success. The same year, Heigl landed the starring role of Karly Hert in the independent film Side Effects, about marketing and the pharmaceutical industry. In late 2006, Heigl was nominated for a Golden Globe award in the category, Best Supporting Actress in a Series, Mini-series, or Motion Picture Made for Television for her work on Grey's. Also in 2006, she filmed Knocked Up, a comedy from writer/director Judd Apatow, starring opposite Seth Rogen. Upon its June 2007 theatrical release, the film received largely positive reviews from critics, and proved to be a box office success.

Heigl has portrayed three characters named on some variation of the name "Isabel." Heigl has joked in interviews that she must have been named Isabel in a past life. She has been on FHM's "100 Sexiest Women in the World" list twice as of 2007.

Katherine Marie Heigl